If you are thinking about consuming meth through snorting, smoking, or injecting, you should know that meth has a negative impact on your brain’s dopamine receptors. Meth can stimulate each with an overwhelming rush of the brain chemicals. In turn, you will experience an increase in energy and mood.
- Dopamine is linked to the brain’s reward centers, which explains why the use of meth can cause drug dependence and addiction.
- It has been proven to come with neurotoxic effects on the dopamine neurons which also induces symptoms just like Parkinson’s disease in long-time meth users.
Meth use may cause dangerous health problems over time.
The statement is true whether you eat meth or make use of other routes. Chronic use is known to lead to delusions, paranoia, repetitive behavior, and hallucinations as if parasites or crawling insects are underneath your skin. Chronic meth users often have scratches on their skin, which have become an obsession.
In particular, those who eat this drug often suffer a teeth degeneration, which is medically termed as “meth mouth.” The condition is believed to be a result of combining “dry mouth,” grinding of the teeth and poor oral hygiene. Meth users also suffer from a decrease in appetite and sleep resulting to a subsequent weight loss and a quick deterioration of their physical appearance.
Methamphetamine hydrochloride is the main ingredient that is used in meth.
It is a chemical with a light yellow crystalline powder that is sometimes presented as a large, clear crystal of very high purity. Oftentimes known as “ice,” it comes in a number of forms.
The free base meth or methamphetamine base comes in a liquid form and is the initial product of the drug. It is usually sold at room temperature. Hydrochloride salt comes from a free base form often by bubbling the hydrogen chloride in a gas state. Additionally, methamphetamine contains an optically active carbon atom.
There are 2 isomeric forms of the drug known as the l-methamphetamine and the d-methamphetamine. The l-isomer is less potent than the d-isomer, but the latter is the most produced by many illicit labs. D-methamphetamine in the U.S. is a controlled substance made available only by obtaining a prescription for legal medical purposes, which is often to treat ADHD and obesity.
Methamphetamine is usually absorbed through your GI tract by approximately 4 to 6 hours.
The duration of its effects can last for 6-12 hours or up to one day if taken in larger doses. The peak plasma levels of the drug, on the other hand, can be obtained in 1-3 hours depending on the physical activities you do and the food you eat.
The peak blood concentrations of meth can happen shortly after injecting, several minutes after smoking and about 3 hours after dosing orally. The peak concentrations of meth following oral administration is around 2.6 to 3.6 hours. Thus, the mean elimination half-life of the drug is around 10.1 hours if you follow the 6.4 to 15 hours range. The mean elimination half-life of meth following intravenous injection may be a little bit longer at 12.2 hours.
The effects of methamphetamine use on humans can be profound.
As a stimulant, the effects of the drug can linger for hours with the meth user staying awake for several days. Once the high starts to wear off, the user enters a stage known as tweaking and becomes more prone to delusions, paranoia, and violence.
The use of meth can easily lead to addiction because of its euphoric effect. Those who abuse meth may need to use more of the drug to reach the same effects. Your psychological need for the drug may compel you to continually use the drug especially if you have underlying unresolved psych-emotional issues.